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. 2017 Sep 29;5(10):E959–E973. doi: 10.1055/s-0043-117958

Table 1. Summary of evidence by comparison investigated and study methodology.

Comparator RCTs [ref] NRSIs [ref] Ongoing trials
Choice of investigation
Flexible sigmoidoscopy vs. CTA None None
Flexible sigmoidoscopy vs. other None None
Colonoscopy vs. CTA None Nagata 2015 26 Yabutani 2014 21
Colonoscopy vs. other (e. g. standard care) Green 2005 4 Yamaguchi 2006 23
CTA vs. other None Ketwaroo 2012 18 Sun 2011 20 Jacovides 2015 25
Diagnostic mesenteric angiography vs. other None None
Timing of first-line investigation
Colonoscopy: Early (< 24 hours) vs. late (> 24 hours) Laine 2010 Abeldawi 2014 24 Nagata 2016 27 Strate 2003 28 Rodriguez-Moranta 2007 19
Radiology: A) Urgent CTA vs. nonurgent B) Urgent mesenteric angiography vs. nonurgent None None None None
Choice of treatment
Therapeutic endoscopy vs. mesenteric embolization None None
Therapeutic endoscopy vs. other None Jensen 2000 30 Matsuhashi JPRN-UMIN000008287
Embolization vs. other None None
Endoscopic agent A vs. B None Nakano 2015 22 Ishii 2011 17 Barkun NCT02135627

RCT, randomized controlled trials; NRSI, nonrandomized studies of intervention; CTA, computed tomographic angiography.