Figure 3.

Regulatory microRNAs targeting connexin gene transcripts. Schematic illustrating different microRNAs targeting the expression of specific connexin molecules demonstrated herein. The most widely studied Cx43 is experimentally shown to be targeted by several different miRNAs in various tissues (Right side panel). Left side panel represents different connexins in islets and bioinformatically identified, highly conserved (using the publically available site http://www.targetscan.org) microRNAs predicted to bind to a specific connexin.