Figure 4.

Plots of real cone bipolar cell mosaics appear similar to those of random distributions. a–d: Mosaics of horizontal cells (a), cholinergic amacrine cells (b), Type 2 cone bipolar cells (c) and Type 4 cone bipolar cells (d), from B6/J (top, in red) and A/J mice (bottom, in green). Beneath each real mosaic is a simulation of a random distribution of cells matched in density and constrained by soma size (shown in desaturated color). All fields illustrated here are of the same area, and each cell portrayed in the real mosaic and in the simulation is depicted with a dot scaled to the average soma size for that cell type, to ease comparisons between the cell types. While the two strains vary in the degree of their difference in density for these four cell types, the patterning of their mosaics is comparable between the strains, yet distinct for the different cell types. Calibration bar = 50 μm.