Table 2.

Subgroup analysis of ⁶⁸Ga-NOTA-PRGD2 and ¹⁸F-FDG PET imaging.

Group	Total	RGDmax					FDGmax
		Lesion	Contralateral	p	LCR		Lesion	Contralateral	p	LCR
Overall	N=21	0.15 (0.05–0.64)	0.06 (0.03–0.11)	0.001	2.6 (0.75–10.67)		11.28 (2.73–21.11)	13.92 (6.44–26.77)	0.001	0.92 (0.21–10.05)
Qualifying infarction*
Yes	N=7	0.17 (0.11–0.64)	0.06 (0.03–0.07)	0.017	3.00 (2.00–10.67)		5.52 (2.73–11.09)	13.92 (7.37–26.77)	0.018	0.53 (0.21–0.85)
No	N=14	0.155 (0.06–0.29)	0.06 (0.03–0.11)	<0.003	2.81 (1.50–4.00)		12.76 (5.79–21.11)	13.5 (6.44–21)	0.069	0.96 (0.87–1.05)
Severity of the qualifying artery
O	N=15	0.16 (0.06–0.64)	0.06 (0.03–0.11)	0.001	3.00 (0.75–10.67)		11.09 (2.73–21.11)	14.37 (6.5–26.77)	0.005	0.92 (0.21–1.04)
S	N=6	0.13 (0.06–0.21)	0.06 (0.05–0.10)	0.042	1.90 (1.00–2.63)		12.17 (4.96–16.23)	13.28 (6.44–18.69)	0.116	0.93 (0.36–1.05)
Months from qualifying event to PET scans**
<6 m	N=4	0.24 (0.13–0.64)	0.05 (0.03–0.06)	0.125	6.73 (2.60–10.67)		6.53 (2.73–13.30)	14.15 (7.37–15.42)	0.125	0.47 (0.36–0.86)
>6 m	N=10	0.14 (0.09–0.21)	0.06 (0.03–0.11)	0.007	2.36 (0.90–3.67)		11.19 (4.3–17.23)	12.47 (6.5–26.77)	0.017	0.89 (0.21–1.05)

LCR: lesion to contralateral ratio; O: occlusion; S: stenosis; FDG_max: maximum value of ¹⁸F-fluorodeoxyglucose; RGD_max: radiolabeled cyclic arginine-glycine-aspartic acid. The values in parentheses indicate the range for the data. *p<0.001, FDG_max LCR comparison between subjects with a qualifying infarction and those without infarction; **p=0.014 and p=0.052, RGD_max LCR and FDG_max LCR between the recent (<6 m) vs. remote (>6 m) groups, respectively.