Figure 4. N1 glycine N-methylation does not prevent binding to CD13+ human umbilical vein cells (HUVEC).

Binding of N1 and MeN1 coupled to fluorescent Qdot605 nanoparticles (6 nM, 2h) to cultured HUVEC (see Supporting Information). None-Qdot corresponds to nanoparticles activated with sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate (sulfo-SMCC), but lacking the peptide.

Magnification, 400X; bar, 20 µm; red, Qdots; blue, nuclear staining with 4′,6-diamidine-2′-phenylindole dihydrochloride (DAPI).