Table 2.
Cox regression analyses model of baseline predictors for HIV patients followed from 2010 to 2015 at general hospitals of Central Zone, Tigray, northern Ethiopia
| Variable (n=638) | Category | Patient outcome
|
CHR (95% CI) | AHR (95% CI) | |
|---|---|---|---|---|---|
| Censored
|
Died
|
||||
| N (%) | N (%) | ||||
| Baseline CD4 cell count (cells/mm3) | ≥350 | 314 (98.4) | 5 (1.6) | 1 | 1 |
| <350 | 276 (86.5) | 43 (13.5) | 8.47 (3.35–21.38) | 3.22 (1.17–8.82) | |
| Sex | Male | 178 (89.5) | 21 (10.5) | 1.92 (1.08–3.39) | 1.68 (0.86–3.31) |
| Female | 412 (93.8) | 27 (6.2) | 1 | 1 | |
| Residence | Urban | 433 (95.4) | 21 (4.6) | 1 | 1 |
| Rural | 157 (85.3) | 27 (14.7) | 3.56 (2.01–6.31) | 1.96 (1.05–3.68) | |
| Marital status | Unmarried | 125 (91.2) | 12 (8.8) | 1 | NI |
| Married | 307 (93.9) | 20 (6.1) | 0.57 (0.28–1.18) | NI | |
| Divorced or widowed | 158 (90.8) | 16 (9.2) | 0.92 (0.43–1.94) | NI | |
| Occupation | Employed | 173 (97.2) | 5 (2.8) | 1 | 1 |
| Unemployed | 417 (90.7) | 43 (9.3) | 3.76 (1.49–9.49) | 2.70 (1.03–7.08) | |
| Presence of any OI | No | 52 (78.8) | 14 (21.2) | 1 | 1 |
| Yes | 538 (94.1) | 34 (5.9) | 3.75 (2.01–6.98) | 0.74 (0.37–1.46) | |
| Baseline functional status | Working | 500 (96.7) | 17 (3.3) | 1 | 1 |
| Ambulatory | 66 (78.6) | 18 (21.4) | 7.53 (3.88–14.63) | 2.54 (1.05–6.15) | |
| Bedridden | 24 (64.9) | 13 (35.1) | 12.78 (6.20–26.33) | 2.98 (1.45–6.13) | |
| Baseline hemoglobin level | ≥11 mg/dL | 497 (96.9) | 16 (3.1) | 1 | 1 |
| <11 mg/dL | 93 (74.4) | 32 (25.6) | 9.95 (5.45–18.15) | 3.06 (1.51–6.23) | |
| Baseline weight (kg) | <40 | 44 (70.8) | 18 (19.2) | 5.54 (2.20–13.97) | 1.95 (0.68–5.56) |
| 40–60 | 449 (94.9) | 24 (5.1) | 0.89 (0.36–2.17) | 0.66 (0.26–1.66) | |
| >60 | 97 (94.2) | 6 (5.8) | 1 | 1 | |
| Baseline WHO stage | I and II | 396 (98.0) | 8 (2.0) | 1 | NI |
| III and IV | 194 (82.9) | 40 (17.1) | 9.45 (4.43–20.20) | NI | |
Note: Data shown in bold indicates statistical significance (P<0.05).
Abbreviations: AHR, adjusted hazard ratio; CD4 cells, cluster of differentiation 4 cells; CHR, crude hazard ratio; CI, confidence interval; HIV, human immunodeficiency virus; NI, not included; OI, opportunistic illness; WHO, World Health Organization.