Table 2. M1:M2 ratio of mean fold change of macrophage mRNA markers.

M1 markers	M1:M2 ratio
Tumour necrosis factor alpha (TNF-α)	18.12
Interleukin 12β (IL-12β)	9.66
prostaglandin-endoperoxide synthase 2 (PTGS2, also known as Cox2)	13.40
M2 markers	M1:M2 ratio
Interleukin-10 (IL-10)	0.16
CD200R	0.41
C-type mannose receptor 1 (MRC-1, also known as CD206)	0.04
Transglutaminase 2 (TGM-2)	0.34

M1: M2 ratio of mean fold change of each M1 or M2 specific macrophage marker in healthy human peripheral blood MDM. M1 phenotype MDM were generated by stimulation of MDM with 10ng/mL LPS plus 20ng/mL IFNγ for 24 hours, and M2 phenotype MDM generated by stimulation of MDM with 20ng/mL IL-4 for 24 hours (M2). Values are expressed to nearest 2 decimal places and presented as mean fold change for 5 independent experiments.