Table 3. Phenotype probabilities for different levels of expression and DNA damage S for node miR16.
phenotype | KD | O1 | O2 | ||||||
---|---|---|---|---|---|---|---|---|---|
S | 0 | 1 | 2 | 0 | 1 | 2 | 0 | 1 | 2 |
proliferation | 1.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
apoptosis | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.0 | 0.0 | 0.0 | 1.0 |
senescence | 0.0 | 0.0 | 1.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
trans. arrest | 0.0 | 1.0 | 0.0 | 1.0 | 1.0 | 0.0 | 1.0 | 1.0 | 0.0 |
KD: knockdown; O1: median expression (miR16 = 1). O2: overexpression (miR16 = 2).