Table 1. Epidemiological, clinical and radiographic findings for patients presenting with enteric fever, according to pathogen (Salmonella Typhi versus Salmonella Paratyphi A).
| N | Salmonella Typhi | N | Salmonella Paratyphi A | Significant p-values | |
|---|---|---|---|---|---|
| Epidemiology (numbers (% of total)) | |||||
| Male | 64 | 32 (50) | 190 | 93 (48.9) | |
| Phnom Penh resident | 63 | 38 (60.3) | 189 | 154 (81.5) | 0.001 |
| Hospitalization | 63 | 11 (17.5) | 188 | 19 (10.1) | |
| Previous antibiotic exposurea | |||||
| Epidemiology (median (IQR)) | |||||
| Median age, years | 64 | 23 (18–30) | 190 | 26 (22–31) | 0.015 |
| Median duration of symptoms, days | 40 | 4 (3–7) | 112 | 4 (3–7) | |
| Median duration of hospitalization, days | 10b | 5.5 (3–6) | 19 | 4 (2–5) | |
| Symptom and signs (numbers (% of total)) | |||||
| Fever | 48 | 48 (100) | 182 | 181 (99.5) | |
| Abdominal pain | 48 | 30 (62.5) | 182 | 113 (62.1) | |
| Diarrhea | 48 | 12 (25.0) | 182 | 40 (22.0) | |
| Constipation | 48 | 4 (8.3) | 182 | 10 (5.5) | |
| Vomiting | 48 | 11 (22.9) | 182 | 27 (14.8) | |
| Headache | 43 | 24 (55.8) | 178 | 114 (64.0) | |
| Cough | 40 | 15 (37.5) | 168 | 46 (27.4) | |
| Physical findings (median (IQR)) | |||||
| Temperature, °C | 46 | 38.4 (37.3–39.0) | 179 | 38.0 (37.0–38.8) | |
| Pulse, beats/min. | 46 | 106 (95–119) | 179 | 105 (91–117) | |
| Systolic blood pressure, mm Hg | 46 | 107 (100–117) | 179 | 113 (103–123) | 0.036 |
| Diastolic blood pressure, mm Hg | 46 | 67.5 (60–77) | 179 | 70 (64–78) | |
| Physical findings (numbers (% of total)) | |||||
| Fever (Temperature >38°C) | 46 | 26 (56.5) | 179 | 88 (49.2) | |
| Tachycardia (Pulse >100 beats/min)c | 46 | 27 (58.7) | 179 | 109 (60.9) | |
| Abdominal tenderness | 39 | 15 (38.5) | 164 | 56 (34.1) | |
| Radiographic signs | |||||
| Ultrasound: Splenomegaly | 11 | 3 (27.3) | 38 | 5 (13.2) | |
| Ultrasound: Hepatomegaly | 11 | 0 (0) | 38 | 6 (15.8) | |
| Chest X-ray: Normal | 10 | 9 (90.0) | 32 | 31 (96.9) | |
For statistical analysis the X2 test or Fisher exact test was used for proportions and the Mann-Whitney U test for continuous variables. Only statistically significant p-values are listed
IQR = Interquartile range
a = Two weeks before presentation
b = Data on duration of hospitalization was missing for one Salmonella Typhi patient
c = For children aged 5–12 years (N = 4) tachycardia was defined as >120 beats/min