Table 2. Laboratory parameters at presentation for enteric fever patients attending the Sihanouk Hospital Center of HOPE in Phnom Penh, Cambodia.
| N | Salmonella Typhi | N | Salmonella Paratyphi A | Significant p-values | |
|---|---|---|---|---|---|
| Values expressed as median (IQR) | |||||
| Hemoglobin, g/L | 60 | 13.1 (12.1–14.2) | 186 | 13.2 (12.2–14.5) | |
| Leukocyte count, cells x 109/L | 60 | 6.8 (5.6–8.8) | 186 | 6.3 (5.1–7.6) | 0.035 |
| Monocyte count, cells x 109/L | 12 | 0.33 (0.28–0.55) | 41 | 0.48 (0.37–0.72) | |
| Eosinophil count, cells x 109/L | 12 | 0 (0–0.01) | 41 | 0 (0–0.03) | |
| Basophil count, cells x 109/L | 12 | 0.02 (0.01–0.03) | 40b | 0.01 (0.01–0.02) | |
| Thrombocyte count, cells x 109/L | 52 | 205 (166–251) | 185 | 205 (165–247) | |
| CRP, mg/L | 13 | 47.0 (38.6–79.2) | 43 | 36.0 (25.2–54.7) | 0.034 |
| AST, units/L | 40 | 47.0 (33.5–81.5) | 148 | 43.0 (30.5–72.5) | |
| ALT, units/L | 40 | 38.5 (26–88) | 148 | 39.0 (24.5–72.5) | |
| Sodium mmol/L | 33 | 132 (130–135) | 105 | 135 (132–137) | 0.024 |
| Potassium mmol/L | 33 | 3.9 (3.7–4.2) | 105 | 3.9 (3.6–4.1) | |
| Chloride mmol/L | 32 | 99 (96–101) | 105 | 100 (97–102) | |
| Values expressed as numbers (% of total) | |||||
| Leukocytosis (leukocytes >11 x109/L) | 60 | 6 (10) | 186 | 4 (2.2) | 0.015 |
| Leukopenia (leukocytes <4x109/L) | 60 | 4 (6.7) | 186 | 17 (9.1) | |
| Eosinopenia (eosinophils <0.08x109/L) | 13 | 13 (100) | 41 | 36 (87.8) | |
| Thrombocytopenia (<150x109L) | 52 | 11 (21.2) | 185 | 31 (16.8) | |
| Elevated AST and/or ALT (units/L)a | 40 | 28 (70.0) | 148 | 105 (70.9) | |
For statistical analysis the X2 test or Fisher exact test was used for proportions and the Mann-Whitney U test for continuous variables. Only statistically significant p-values are listed
ALT = Alanine transaminase
AST = Aspartate transaminase
CRP = C-reactive protein
IQR = Interquartile range
a = ≥ 18 years: Males: AST ≥35U/L and ALT ≥45U/L; Females: AST ≥31U/L and ALT ≥34U/L; 13–17 years: AST ≥42U/L and ALT ≥45U/L; 7–12 years: AST ≥48U/L and ALT ≥44U/L
b = Basophil count not measurable in 1 patient