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. Author manuscript; available in PMC: 2018 Mar 29.
Published in final edited form as: Tetrahedron Lett. 2017 Feb 12;58(13):1276–1279. doi: 10.1016/j.tetlet.2017.02.033

Table 2.

Optimization of reaction conditions for substituted cyclic 2-aminoquinazoline derivatives.

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entry acid/base equivalent solvent yields (%)a
1 PTSA 1 DMF 66
2 KOtBu 1 DMF 78
a

Isolated Yields (Flash Chromatography).