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. Author manuscript; available in PMC: 2017 Oct 2.
Published in final edited form as: Biochemistry. 2012 Aug 3;51(32):6342–6349. doi: 10.1021/bi3007687

Figure 4.

Figure 4

A) Analytical vs. continuous flow cross-linking of Aβ40 and Aβ42. The leftmost lanes are non-cross-linked protein (XL), the middle lanes are analytical scale cross-linking (A), and the rightmost lanes are 0.2 ml/min continuous flow cross-linking (CFR), these data from Fig. 3 are shown here side-by-side for clarity of comparison. The number of monomers per oligomer is shown on the right. B) Densitometry analysis of oligomer abundance for analytical vs. continuous flow cross-linking. Oligomer order is plotted vs. oligomer frequency. Black bars show abundance from the analytical scale system. White bars represent the abundance from the continuous flow system.