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. Author manuscript; available in PMC: 2017 Oct 2.
Published in final edited form as: Free Radic Biol Med. 2015 Jul 9;89:8–19. doi: 10.1016/j.freeradbiomed.2015.07.005

Fig. 8.

Fig. 8

MGO targets the cytosolic Trx/TrxR system. Trx1 (A) and TrxR1 (D) expression in HT22 cells expose to MGO, and their respective quantification (B and E). Activities of Trx (C) and TrxR (F) are also presented. Densitometric data were normalized to actin content and expressed as percentage of untreated control. Enzymatic activity was quantified as described under Materials and methods and presented relative to untreated control (dashed line). Data on graphs are presented as means + SEM (N=4–9). P<0.01 (**) or < 0.001 (***) indicate significant differences relative to untreated control (dashed lines).