Table 2.

Potential Angiogenic Therapy

Potential Angiogenic Therapy	Proposed Mechanism of Action	Planned Clinical Trials (Y/N)
Calpain/GSK3B inhibition	Improved myocardial perfusion, reduced apoptosis, increased microvascular relaxation, reduced oxidative stress	Y
Neuropeptide Y injection	Improved collateral vessel growth	Y
GM-CSF injection	Increased coronary collateral arterial growth	Y
VEGF Therapy	Increased macrophage levels in bone marrow and peripheral blood	Y
Endothelial progenitor therapy	Inhibits neointimal hyperplasia	Y
Stem Cell Therapy	Improved neovascularization and blood-flow recovery in ischemic myocardial tissue	Y