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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: J Stroke Cerebrovasc Dis. 2017 Jun 23;26(11):2553–2562. doi: 10.1016/j.jstrokecerebrovasdis.2017.05.041

TABLE 2.

Comparison of demographic and clinical features of Stroke survivors according to Vascular cognitive Impairment status.

VARIABLES Stroke with no
VCI, n=77
VCI no dementia,
n=50
Post-stroke
Dementia, n=20
P-value A vs B A vs C B vs C A vs B+C
Age 55.5 ± 11.8 63.5 ± 14.5 67.8 ± 12.8 <0.0001 0.001 <0.0001 0.26 <0.0001
Female gender 30 (39.0) 25 (50.0) 11 (55.0) 0.29 0.22 0.2 0.71 0.13
Educational Status
None 3 (3.9) 13 (26.0) 6 (30.0) 0.0015 0.0017 0.001 0.15 0.0007
Primary 25 (32.5) 9 (18.0) 8 (40.0)
Secondary 38 (49.4) 19 (38.0) 3 (15.0)
Tertiary 11 (14.3) 8 (16.0) 3 (15.0)
Location of residence 0.9 0.98 0.61 0.58 0.94
Rural 3 (3.9) 2 (4.0) 0 (0.0)
Semi-urban 22 (28.6) 15 (30.0) 5 (25.0)
Urban 52 (67.5) 33 (66.0) 15 (75.0)
Stroke type 0.43 0.48 0.37 0.32 0.52
Ischemic 49 (63.6) 32 (64.0) 16 (80.0)
Hemorrhagic 19 (24.7) 9 (18.0) 3 (15.0)
Unknown 9 (11.7) 9 (18.0) 1 (5.0)
Duration of stroke (years)
mean ± SD 2.7 ± 2.1 3.7 ± 4.3 1.7 ± 4.3 0.06 0.08 0.14 0.09 0.31
NIHSS, mean ± SD 3.9 ± 4.9 6.9 ± 5.7 14.6 ± 7.8 <0.0001 0.003 <0.0001 <0.0001 <0.0001
MRS, mean ± SD 1.5 ± 1.0 2.5 ± 1.2 4.2 ± 0.5 <0.0001 <0.0001 <0.0001 <0.0001 <0.0001
Barthels Index 92.7 ± 15.8 83.1 ± 18.0 39.5 ± 15.2 <0.0001 0.002 <0.0001 <0.0001 <0.0001
CES-D score 18.7 ± 7.3 20.3 ± 5.8 19.5 ± 4.8 0.41 0.2 0.66 0.34 0.21
Vascular Risk Factors
Hypertension 71 (92.2) 49 (98.0) 18 (90.0) 0.31 0.16 0.75 0.14 0.38
Diabetes Mellitus 17 (22.1) 16 (32.0) 8 (40.0) 0.2 0.22 0.1 0.52 0.1
Dyslipidemia 37 (48.1) 18 (36.0) 10 (50.0) 0.35 0.18 0.88 0.28 0.03
Alcohol intake 25 (32.5) 10 (20.0) 1 (5.0) 0.03 0.12 0.01 0.12 0.06
Cigarette smoking 5 (6.5) 3 (6.0) 0 (0.0) 0.51 0.91 0.24 0.26 0.47
Physical inactivity 33 (42.9) 16 (32.0) 3 (15.0) 0.06 0.22 0.02 0.15 0.05
Heart disease 0 (0.0) 0 (0.0) 3 (15.0) <0.0001 1 0.0006 0.005 0.07
BMI 26.7 ± 8.0 27.5 ± 4.9 25.6 ± 4.8 0.60 0.90 0.14 0.15 0.60
HRQOLISP
Physical domain 18.9 ± 3.5 18.5 ± 3.3 17.2 ± 3.5 0.13 0.51 0.05 0.13 0.16
Psychosocial domain 23.6 ± 3.9 21.3 ± 4.5 18.2 ± 3.4 <0.0001 0.001 <0.0001 0.001 <0.0001
Cognitive domain 21.1 ± 3.6 18.8 ± 3.8 14.7 ± 5.0 <0.0001 0.001 <0.0001 0.0003 <0.0001
Eco-social domain 29.2 ± 4.3 25.5 ± 4.0 21.7 ± 4.4 <0.0001 <0.0001 <0.0001 0.0007 <0.0001

A = Stroke with no VCI, B = VCI no dementia, C = Post-stroke Dementia, VCI = Vascular Cognitive Impairment, NIHSS