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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Radiother Oncol. 2017 Aug 1;124(3):468–474. doi: 10.1016/j.radonc.2017.07.018

Figure 5.

Figure 5

Intestinal tissue damage assessment and marrow and tissue SDF-1 expression in mice receiving TBI versus TMI, 3 days after HCT. A. Intestinal histology and measured villus height and crypt depth. B. Tissue SDF-1 measurement by IHC is presented for various organs. The derived ratios of SDF-1 in organs with respect to bone marrow are also presented. A schematic presentation showing, for TBI, increased SDF-1 chemokine gradient towards the peripheral niche compared to the BM niche, attracting migratory donor cells from blood to organs; for TMI the reverse migration occurs, with higher chemokine gradient towards the BM niche.