(A) Graphical representation for the assembly of mechanized MSNPs. (B) Schematic model and TEM image of UCNP@mSiO2 nanoparticles (1), the schematic illustrationof the drug release from DOX-UCNP@mSiO2-Ru nanoparticles (2). (C) Synthetic scheme for the pSiNP–Ru–PEG–Man. (D) The reaction pathways for the construction of the materials RuPOP@MSNs. Reproduced with permission from ref. 290 (Copyright 2015, American Chemical Society), 291, 292 (Copyright 2012, Royal Society of Chemistry) and 293 (Copyright 2015, Wiley-VCH), respectively.