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. Author manuscript; available in PMC: 2018 Oct 2.
Published in final edited form as: Chem Soc Rev. 2017 Oct 2;46(19):5771–5804. doi: 10.1039/c7cs00195a

Table 1.

The cytotoxicity of the selective cycloruthenated compounds used in anticancer drugs

Compounds Cell lines IC50 (μM) Ref.
13a A172 > 50 223
13b A172 1.9 223
13c A172 12 223
13d A172 15 227
13e A172 > 50 227
13f A172 12 227
13g A172 6.0 227
13h A172 9.0 227
13i A172 > 50 227
13j A172 15 227
13k HCT116 > 50 228
13l HCT116 0.1 228
13m HCT116 5.0 228
13n HCT116 0.2 228
13o HCT116 0.5 228
13p HeLa 57 230
13q HeLa 51 230
13r HeLa 2.4 233
13s HeLa 34 230
13t HeLa 6.1 231
13u HeLa 3.4 231
13v HeLa 3.7 80
13w HeLa 2.0 213
13x HeLa 7.0 230
13y HCT116 1.4 228
13y-1 HCT116 0.7 228
13y-2 HCT116 2.5 228
13y-3 HCT116 1.0 228
13y-4 HCT116 0.3 228
13y-5 HeLa 0.51 232
13y-6 HeLa 1.05 232