A. Approximately 0.5 μg KDAC8 (42.5 kDa) purified from either insect cells (lane 2) or E. coli (lane 3) was compared by gel electrophoresis on a 12.5% SDS-PAGE gel, indicating similar purity from both expression systems. B. Approximately 1.5 μg purified KDAC8 (lane 2), KDAC7 (lane 3, 46 kDa), and KDAC4 (Lane 4, 48 kDa) are shown on a 12.5% SDS-PAGE gel. C. Approximately 1 μg KDAC6-His6 (134 kDa) is shown on a 10% SDS-PAGE gel.