Table 1.

The experimental data obtained for the three responses based on the CCD matrix

Run no	Type	Temperature (X 1)	Time (X 2)	Solvent ratio (X 3)	Phenolic content mg/g GAE	Flavonoid content mg QE/g extract
1	Fact	80.0	80.0	90.0	131.96	6.18
2	Fact	60.0	120.0	70.0	116.76	6.00
3	Center	70.0	100.0	80.0	122.20	6.24
4	Fact	80.0	120.0	70.0	122.90	6.07
5	Axial	53.18	100.0	80.0	116.14	6.09
6	Center	70.0	100.0	80.0	122.64	6.23
7	Axial	70.0	66.36	80.0	115.32	6.31
8	Axial	86.82	100.0	80.0	135.77	6.05
9	Axial	70.0	100.0	96.82	119.17	6.35
10	Fact	80.0	80.0	70.0	121.80	6.21
11	Axial	70.0	100.0	63.18	105.10	6.06
12	Fact	80.0	120.0	90.0	122.43	6.22
13	Fact	60.0	80.0	70.0	98.76	6.08
14	Fact	60.0	80.0	90.0	115.83	6.33
15	Center	70.0	100.0	80.0	122.32	6.23
16	Center	70.0	100.0	80.0	122.24	6.21
17	Fact	60.0	120.0	90.0	122.30	6.38
18	Axial	70.0	133.64	80.0	122.27	6.26
19	Center	70.0	100.0	80.0	122.55	6.22
20	Center	70.0	100.0	80.0	122.25	6.23