Table 2.

Analysis of variance (ANOVA) for the model

Sources	Sum of squares	Degree of freedom	Mean squares	F-value	p-value
Phenolic content (mg/g GAE)
Model	1191.21	9	132.36	1662.76	< 0.0001
X 1-temperature	450.69	1	450.69	5661.84	< 0.0001
X 2-Time	56.30	1	56.30	707.27	< 0.0001
X 3-solvent ratio	229.32	1	229.32	2880.92	< 0.0001
X 1 X 2	135.30	1	135.30	1699.75	< 0.0001
X 1 X 3	20.87	1	20.87	262.13	< 0.0001
X 2 X 3	61.38	1	61.38	771.14	< 0.0001
X 21	25.87	1	25.87	325.02	< 0.0001
X 22	20.46	1	20.46	257.06	< 0.0001
X 23	181.23	1	181.23	2276.79	< 0.0001
Residual	0.80	10	0.080
Lack of fit	0.63	5	0.13	3.74	0.0870
Pure error	0.17	5	0.034
Cor total	1192.01	19
R2 = 0.9993 Adj. R2 = 0.9987 CV% = 0.24
Flavonoid content (mg QE/g of extract)
Model	0.22	9	0.024	229.66	< 0.0001
X 1-temperature	0.002	1	0.002	21.86	0.0009
X 2-Time	0.003	1	0.003	31.89	0.0002
X 3-solvent ratio	0.11	1	0.11	1065.88	< 0.0001
X 1 X 2	0.0006	1	0.0006	5.82	0.0365
X 1 X 3	0.033	1	0.033	308.93	< 0.0001
X 2 X 3	0.012	1	0.012	114.14	< 0.0001
X 21	0.044	1	0.044	421.70	< 0.0001
X 22	0.0006	1	0.0006	57.66	< 0.0001
X 23	0.0008	1	0.0008	8.25	0.0166
Residual	0.001	10	0.0001
Lack of fit	0.0005	5	0.0001	0.97	0.5115
Pure error	0.0005	5	0.0001
Cor total	0.22	19
R2 = 0.9952 Adj. R2 = 0.9909 CV% = 0.17