Table 2.
In vivo inhibition of KD50 of 2,3-dimethylmaleic anhydride on acetlycholinesterase in neural ganglion of P. americana and S. oryzae homogenate at different exposure.
Exposure period (min) | % of AChE inhibition (mean ± SE) | |||
---|---|---|---|---|
P. americana | S. oryzae | |||
Control | Treated | Control | Treated | |
30 | 2.1 ± 0.4a | 40.5 ± 2.4a | 2.4 ± 0.2a | 47. 2 ± 2.4a |
60 | 4.2 ± 0.2b | 80.3 ± 2.2b | 6.3 ± 0.4b | 63.2 ± 1.8b |
90 | 5.8 ± 0.5c | 90.2 ± 3.4c | 7.2 ± 0.4c | 87.4 ± 1.2c |
120 | 8.3 ± 0.4d | 98 ± 2.2d | 8.8 ± 0.6d | 90. 1 ± 3.2cd |
150 | 10.2 ± 1.2e | 98.2 ± 2.4de | 13.6 ± 2.4e | 96.8 ± 1.2e |
The values were expressed within a column indicate that mean ± standard error of four replicates and significantly different (P < 0.05) by Newman-Keuls test.