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. 2017 Oct 2;7:12492. doi: 10.1038/s41598-017-12666-z

Figure 9.

Figure 9

Experimental model to characterize the effect of mast cells in the IVD microenvironment. Conditioned media from activated mast cells was applied to 3D in vitro constructs containing NP, AF, or EP cells. Healthy and degenerate IVD cell conditioned media (NP, AF, EP) was applied to mast cells in suspension.