Table 3.

Results of TDT association testing for the SNPs evaluated in the UK cohort. Only the top four hits are shown, data for all SNPs tested are shown in Supplementary Table S1. MAF = Minor Allele Frequency.

Locus	SNP	Genomic coordinate and annotation	p-value	Risk allele	MAF	Odds ratio(95% confidence interval)
TGIF1	rs881835	18:3449312 (intronic)	0.006	T	0.0711	1.388 (1.099–1.769)
TGIF1	rs1962914	18:3426900 (intronic)	0.007	G	0.0290	1.577 (1.140–2.240)
FBXO11	rs10490302	2:47812605 (intronic)	0.016	A	0.3129	1.173 (1.030–1.338)
FBXO11	rs2537742	2:47811905 (intronic)	0.038	G	0.2535	1.156 (1.009–1.328)