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. 2017 Oct 2;7:12508. doi: 10.1038/s41598-017-12863-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Secondary metabolite clusters in behavior manipulating Ophiocordyceps species. (a) Expression profiles of three differentially expressed secondary metabolite clusters in O. kimflemingiae in culture, during manipulated biting behavior, and after manipulation. (b) Homology (identified by BLASTp alignment) and orthology (identified by orthologous clustering) of genes within secondary metabolite cluster 8. Genes that were found using both methods are connected by a black line. Genes found by BLASTp alignment only are connected with a blue line, while genes only found by orthologous clustering are connected with a dashed line. Gene numbers and functions in red indicate genes that received a secondary metabolism annotation.