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. 2017 Oct 2;7:12535. doi: 10.1038/s41598-017-12082-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Cytoprotective effect of compounds (5, 4a–f, and 10) on BV-2 cell lines. The BV2 cells were treated with 100 ng/mL of LPS 30 min after the compounds were treated for 24 h. Cell viability was expressed as a percentage of LPS-treated cells (set as 100%). All the data are presented as the mean ± SEM of three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001 vs. LPS-treated cells.