Table 1.
List of studies included in this review (N = 35).
| First author, year (ref) | N | Indication | Age (years)a | Approach | Method | Follow-up (months) |
|---|---|---|---|---|---|---|
| Fenoy, 2017 (16) | 20 | Tre (ET) | 66.8 ± 10.5 | DTT | D | n.r. |
| Coenen, 2017 (17) | 1 | Tre (ET) | 72 | DTT | D | n.r. |
| O’Holloran, 2016 (18) | 2 | Tre (PD) | 63.0 ± 2.8 | DTT | P | 24 |
| Coenen, 2016 (19) | 2 | Tre (PD) | 75.5 ± 0.7 | DTT | D | 5–8 |
| Coenen, 2012 (20) | 1 | Tre (ET) | 73 | DTT | D | 18 |
| Coenen, 2011a (21) | 1 | Tre (Dys) | 37 | DTT | D | 3 |
| King, 2016 (22) and Sammartino, 2016 (23) | 6b | Tre (ET/PD) | 71.9 ± 5.9 | TPA | P | 12 |
| Coenen, 2014 (24) | 9c | Tre (ET/PD/Dys) | 64.2 ± 17.1 | TPA | D | 3–17 |
| Sweet, 2014 (25) | 7d | Tre (PD) | 62.9 ± 7.3 | TPA | D | n.r. |
| Coenen, 2011b (26) | 1 | Tre (PD) | 73 | TPA | D | 6 |
| Boccard, 2016a (27) | 1 | Tre (post HI) | 20 | TSM | P | 6 |
| Klein, 2012 (28) | 12 | Tre (ET/PD) | 64.8 ± 11.0 | TSM | P | 1–3 |
| Pouratian, 2011 (29) | 6 | Tre (ET) | 69.3 ± 6.1 | TSM | P | n.r. |
| Schweder, 2010 (30) | 1 | FOG (PD) | 56 | TSM | P | n.r. |
| Rozanski, 2014 (31) and Rozanski, 2017 (32) | 10 | Dys | 59.1 ± 13.7 | TSM | P | 2–4 |
| Coenen, 2016 (33) | 2 | OCD | 41.5 ± 13.5 | DTT | D | 12 |
| Makris, 2016 (34) | 1 | OCD | 30 | TPA | P | 6 |
| Hartmann, 2016 (35) | 6 | OCD | 36.2 ± 8.6 | TSM | P | 24 |
| Fenoy, 2016 (36) | 4 | Dep | 46.3 ± 8.9 | DTT | D | 4.5 |
| Schlaepfer, 2013 (37) | 7 | Dep | 42.6 ± 9.8 | DTT | P | 3 |
| Tsolaki, 2017 (38) | 2 | Dep | n.r. | TPA | P | n.r. |
| McNab, 2009 (39) | 1 | Dep | 60 | TSM | D | 12 |
| Accolla, 2016 (40) | 5 | Dep | 45.2 ± 14.4 | TSM | D | 6 |
| Riva-Posse, 2014 (41) | 14 | Dep | 42.0 ± 8.9 | TSM | P | 24 |
| Lujan, 2013 (42) | 1 | Dep | n.r. | TSM | P | 12 |
| Lujan, 2012 (43) | 7 | Dep | 42.4 ± 13.3 | TSM | D | 15–41 |
| Coenen, 2015 (44) | 1 | Pain | n.r. | DTT | D | 15 |
| Hunsche, 2013 (45) | 4 | Pain | 60.8 ± 13.6 | DTT | D | 12 |
| Boccard, 2016b (46) | 8 | Pain | 53.4 ± 6.0 | TSM | P | n.r. |
| Kim, 2016 (47) | 5 | Pain | 56.0 ± 14.8 | TSM | P | 2–48 |
| Kovanliyaka, 2014 (48) | 1 | Pain | 44 | TSM | D | 12 |
| Owen, 2007 (49) and Owen, 2008 (50) | 4 | Pain | n.r. | TSM | P | n.r. |
n.r., not reported.
Indications. Tre, tremor; PD, Parkinson’s disease; ET, essential tremor; Dys, dystonia; HI, head injury; FOG, freezing of gait; OCD, obsessive–compulsive disorder; Dep, depression.
Approaches. DTT, direct tract targeting; TPA, tract proximity analysis; TSM, tract stimulation modeling.
Methods. D, deterministic; P, probabilistic.
aAges are expressed as mean ± SD.
bTwo underwent DBS while four had thalatomy.
cExcluded two patients who also appeared in the study by Coenen et al. (20) and Coenen et al. (21).
dExcluded two patients who did not have tremor symptoms preoperatively.