Figure 5.

Sequence alignments of tandem ZF arrays. A, Hsa Hominidae (great apes/humans) NP_001297143.1 PRDM9 allele B (Thr⁶⁸⁰) (Homo sapiens). (Note that in the NCBI reference sequence, it was named as isoform A; a second sequence, NP_064612.2, was named as isoform B.) For human PRDM9 allele A, B, and C annotation, see Ref. 4. B, Ptr Hominidae (great apes/humans) ACZ82295.1 zinc finger region PR domain-containing 9, partial (Pan troglodytes). C, Mne Cercopithecidae (old world monkeys) XP_011763301.1 PREDICTED: Krueppel-related zinc finger protein 1 isoform X2 (Macaca nemestrina). D, Nle Hylobatidae (gibbons) XP_012365846.1 PREDICTED: Krueppel-related zinc finger protein 1 isoform X7 (Nomascus leucogenys). We note that aside from the fact that the gibbon protein is the best BlastP hit, there is no biochemical proof that it is the PRDM9. The numbers indicate the unique residues at a given position comparing all ZFs in a protein.