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. 2017 Aug 24;292(39):16122–16134. doi: 10.1074/jbc.M117.803973

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Figure 7. — Increasing circulating FLD levels in isolation improves measures of glucose homeostasis in mice fed a HFD. A and B, lower serum glucose levels (A) and lower plasma insulin levels (B) versus Ad-LacZ controls during glucose tolerance testing in Ad-FLD mice fed a HFD for 14 days (n = 6 mice/group). C, reduced hepatic mRNA levels of genes encoding the gluconeogenic enzymes PEPCK (Pepck) and G6Pase (G6pc) in Ad-FLD mice fed a HFD for 3 weeks (n = 5–6 mice/group). *, p < 0.05 versus Ad-LacZ in all cases.