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. 2017 Jul 12;313(3):C340–C351. doi: 10.1152/ajpcell.00249.2016

Fig. 6.

Fig. 6.

OxLDL-induced downregulation of cell cycle regulatory protein p27kip1 is mediated by Akt and Rho. A: representative Western blot image of p27kip1 after 24 h of oxLDL (50 µg/ml) with or without the presence of the Akt inhibitor MK2206. B: densitometric analysis of p27kip1 under corresponding conditions. *P < 0.05, n ≥ 4. C: representative Western blot image of p27kip1 after 24 h of oxLDL (50 µg/ml) with or without the presence of C3. D: densitometric analysis of p27kip1 under corresponding conditions. *P < 0.05, n ≥ 4. E: representative Western blot image of p27kip1 after 24 h of oxLDL (50 µg/ml) with or without the presence of Akt siRNA. F: densiometric analysis of p27kip1 under corresponding conditions. n ≥ 4; markers’ lanes shown in A and E, left. NS, not significant.