Fig. 3.

Renal renin protein expression changes in presymptomatic cardiomyopathy (transgenic). A: Western blot showing expression of renin protein in whole kidney lysates from wild-type (n = 3) and transgenic (n = 2) animals. B: immunohistochemistry showing renin expression largely restricted to the juxta-glomerular apparatus in wild-type kidneys (red arrowhead, n = 5). C: immunohistochemistry showing renin expression in the juxta-glomerular apparatus (red arrowhead) as well as diffusely in tubule epithelial cells in transgenic animals (n = 5).