Urinary K+ (A), plasma K+ (B), urinary Na+ (C), plasma Na+ (D), urinary aldosterone (E), renal cortex aldosterone (F), and renal inner medullary aldosterone (G) in K+-loaded ADX rats treated with or without spironolactone. n = 5 per group. Data are expressed as means ± SE. *P < 0.05, **P < 0.01, and ***P < 0.001.