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. 2017 Sep 28;10:309. doi: 10.3389/fnmol.2017.00309

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Copyright © 2017 Feng, Shao and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The dynamic expression pattern of CHD7 during neurogenesis and oligodendrogenesis. (A) A cartoon shows the expression level of Chd7 transcript during embryonic neurogenesis, based on in situ hybridization data. (B) A cartoon shows the expression level of CHD7 protein in adult neurogenic lineage in hippocampal dentate gyrus, based on immunostaining results. (C) A cartoon shows the increase of CHD7 expression upon differentiation of GNP and OPC, based on immunostaining results. The degree of redness reflects the expression level of Chd7. Arrows show the direction of differentiation. VZ, ventricular zone; SVZ, subventricular zone; IZ, intermediate zone; CP, cortical plate; qNSC, quiescent neural stem cell; aNSC, active NSC; TAP, transit amplifying progenitor; NB, neuroblast; IN, immature neuron; MN, mature neuron; GNP, granule neuron progenitor; CGN, cerebellar granule neuron; OPC, oligodendrocyte precursor cell; OL, oligodendrocyte.