Table 1.
Dosage(mg kg−1) | Survival rate (%) | Molecular weight (Dalton) | Weight of MPP in conjugates (%) | References | |
---|---|---|---|---|---|
GABA | 8000 | 100 | 103 | 0 | |
TD (11aa) | 140 | 100 | 1065 | 100 | |
TAT(11aa) | 27 | 50 | 1560 | 100 | |
CTP(11aa) | 21 | 50 | 1558 | 100 | |
R11(11aa) | 16.5 | 50 | 1735 | 100 | |
GABA –TD | 100 | 100 | 1149 | 92.7 | |
GABA –TAT | 19 | 50 | 1645 | 94.8 | |
GABA –CTP | 13 | 50 | 1644 | 94.8 | |
TAT –ChAT | 339 | 50 | 70000 | 2.2 | |
TAT –hEGF | 0.1 | 100 | 7000 | 22.3 | Zhao et al. (2011a) |
TAT –BDNF | 5 | 100 | 14400 | 10.8 | Zhou et al. (2008); |
TAT –tCNTF | 1 | 100 | 21664 | 7.2 | Qu et al. (2008) |
TAT ‐P53 | 5 | 100 | 54000 | 2.9 | Zhao et al. (2009); Zhao et al. (2011b) |
TAT ‐TH | 8 | 100 | 61000 | 2.6 | Wu et al. (2006); Fu et al. (2006); |
TAT –ChAT | 4 | 100 | 70000 | 2.2 | Fu et al. (2004, 2005) |
MPP, membrane‐permeable peptides; GABA, γ‐aminobutyric acid.