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. 2017 Aug 24;5(5):e00334. doi: 10.1002/prp2.334

Table 2.

Mortality of mice in acute toxicity study (n = 10)

MPPs LD50 (mg kg−1) Groups Control group 1 2 3 4
CTP 21.345 Dose (mg kg−1) 0 19.5 20 20.5 22
Mortality 0/10 2/10 3/10 4/11 6/10
Mortality (%) 0 20 30 36.4 60
TAT 27.244 Dose (mg kg−1) 0 25 27 28 30
Mortality 0/10 2/9 4/9 5/9 7/8
Mortality (%) 0 22.2 44.4 55.6 87.5
R11 16.508 Dose (mg kg−1) 0 15.5 16 16.5 17
Mortality 0/10 1/10 3/10 5/10 7/10
Mortality (%) 0 10 30 50 70
TD >140 Dose (mg kg−1) 0 80 100 140
Mortality 0/10 0/2 0/8 0/8
Mortality (%) 0 0 0 0

MPPs, membrane‐permeable peptides.