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K m and V max kinetic parameters for transporter‐mediated uptake of metformin
| Transporter | Kinetic parameters (±SE) | |
|---|---|---|
| K m (μmol/L) | V max (pmol/min/mg protein) | |
| OCT1 | 5422 ± 369 | 9370 ± 297 |
| OCT2 | 1608 ± 175 | 32918 ± 1165 |
| MATE1 | 4565 ± 903 | 141000 ± 12283 |
| MATE2‐K | 2986 ± 817 | 32147 ± 3401 |
K m, Michaelis–Menten constant; SE, standard error from fitting; V max maximal velocity of uptake.
