Table 5.
Change in renal function parameters from baseline at 2 and 6 months of antituberculosis treatment
| Control group (2 or 6 months value Minus baseline value) | Test group (2 or 6 months value Minus baseline value) | P value | |
|---|---|---|---|
| Month 2 | |||
| Creatinine (mmol/L) | 26.16 (12.75–74.83) | −22.34 (−33.5 to 2.88) | <0.001a |
| Urea (mmol/L) | 4.4 (2.25–5.45) | −1.5 (−3.4 to 0.8) | <0.001a |
| ALB (g/L) | 1.4 (−5.35 to 5.8) | 1.8 (−10.2 to 10) | 0.650 |
| T. protein (g/L) | 2.45 (−6.38 to 13.03) | 0.2 (−13.3 to 8.6) | 0.536 |
| Month 6 | |||
| Creatinine (mmol/L) | 1.65 (−13.99 to 15.42) | −7.58 (−28.7 to 4.53) | 0.051a |
| Urea (mmol/L) | 0.4 (−0.58 to 0.95) | −2 (−3.1 to 0.2) | 0.01a |
| ALB (g/L) | 0 (−6.15 to 6.28) | −0.5 (−6.3 to 7.2) | 0.875 |
| T. protein (g/L) | −0.35 (−9.2 to 5.78) | −3.2 (−10.3 to 2.6) | 0.986 |
a
Mann Whitney U test (Significant); IQR, Interquartile range.
A positive median value of hepatic parameter shows an increase from baseline value, while a negative value indicates a decrease from baseline value.