Arrhythmias in WT and KO animals. A: total ventricular ectopy events over the total net time of 24 h in WT (n = 4) and KO (n = 4) animals. B: average ventricular ectopy events over the total net time of 24 h in WT (n = 4) and KO (n = 4) animals. Mean ± SE values are plotted. NS, not significant. C: ventricular ectopy categories noted over the total net time of 24 h in WT (n = 4) and KO (n = 4) animals. D–I: representative tracings of ventricular arrhythmias noted in WT and KO animals, including premature ventricular contractions [PVCs; WT (D) and KO (E)], couplets (KO; F), three-beat nonsustained ventricular tachycardia (NSVT; KO; G), four-beat NSVT (KO; H), and five-beat NSVT (KO; I).