Fig. 7.
5-HT-induced changes in vessels diameters (A) and cardiovascular parameters (B) in rats infused with SB-269970 or vehicle before pump implantation with 5-HT (25 μg·kg−1·min−1). Measures of blood pressure were done 24 h after pump implantation. Saline + saline animals were used as controls for infusion of vehicles that carried both 5-HT and SB-269970. Points/bars represent means ± SE for the number of animals in parentheses. *Significant from own baseline, ∞significant compared with 5-HT + SB-269970, ±significant compared with saline + saline.