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Nicotine enhances migration of THP-1 cells. THP-1 cells were cultured with MTB, nicotine, or both for 48 hours, and the number of cells that migrated to the lower compartments of the transwells were stained and counted. The microscopic fields shown are representative of the corresponding conditions. The results are expressed as mean (±SD) of two independent experiments. **P < 0.01 compared with control cells (open bar). NS, not significant.
