Table 2. HAstV-positive stool samples: overall and stratified (classical and novel) HAstV patient characteristics.
| All HAstV n=20 | Classical HAstV n=10 | Novel HAstV n=10 | P valuea | |
|---|---|---|---|---|
| Patient characteristics | ||||
| Male sex – no. (%) | 9 (45) | 4 (40) | 5 (50) | |
| Age of pediatric and adult patients (yo) | 0.3258 | |||
| Median (range) | 3.3 (0.06–53.0) | 3.8 (0.5–53.0) | 2.8 (0.06–51.0) | |
| Mean±sd | 12.2±18.6 | 14.0±19.6 | 10.4±18.4 | |
| Pediatric patients, no. (%) | 15 (75) | 7 (70) | 8 (80) | 1.000 |
| Age of pediatric patients, months | 0.3545 | |||
| Median (range) | 16.7 (0.8–57.7) | 16.7 (6.4–57.7) | 19.2 (0.8–50.0) | |
| Mean±sd | 24.4±20.1 | 27.3±21.6 | 21.8±19.8 | |
| Immunocompromised – no. (%) | 9 (45) | 5 (50) | 4 (40) | 1.000 |
| Fever – no. (%) | 7 (36.8)b | 4 (44.4)c | 3 (30) | |
| With respiratory symptoms – no. (%) | 8 (42.1)b | 1 (11.1)c | 7 (70) | 0.020 |
| Time interval between respiratory symptoms and HAstV detection (days) | ||||
| Median (range) | 11.5 (1–20) | 7 | 13 (1–20) | |
| Mean±sd | 11.5±5.9 | 7 | 12.1±6.0 | |
| Time interval between transplantation and HAstV detection (days) | ||||
| Median (range) | 617 (6–1139) | 617 (6–1139) | 626.5 (142–1126) | |
| Mean±sd | 598.1±399.9 | 572.4±428.3 | 630.3±423.6 | |
| HAstV | ||||
| Viral load (RNA copies/mL of resuspended stool) | 0.0007 | |||
| Median (range) | 4.1 × E6 (3.4 × E2–6.0 × E11) | 1.4 × E10 (2.1 × E5–6.0 × E11) | 3.5 × E3 (3.4 × E2–3.3 × E9) | |
| Mean±sd | 3.9 × E10±1.3E × 11 | 7.7 × E10±1.9 × E11 | 3.3 × E8±1.0 × E9 | |
Abbreviations: human astrovirus, HAstV; standard deviation, sd; years old, yo.
a
P-values are for the comparison between the classical and novel HAstV-positive stool sample groups.
b
Percentage calculated based on 19 patients (1 missing data, Table 1).
c
Percentage calculated based on 9 patients (1 missing data, Table 1).