Table 3A.
Description of the clinical and sleep profile of MMSE score decliners.
| N | Modality | Among MMSE decliners | Among non MMSE decliners | ||||
|---|---|---|---|---|---|---|---|
| No EDS | EDS | No EDS | EDS | ||||
| N = 33 | N = 18 | p | N = 299 | N = 68 | p | ||
| Age | (Years) | 75 [70–85] | 74 [70–87] | 0.65** | 74 [70–88] | 73 [70–86] | 0.55 |
| Sex | Women | 20 (60.6%) | 10 (55.6%) | 0.73 | 210 (70.2%) | 41 (60.3%) | 0.11 |
| Men | 13 (39.4%) | 8 (44.4%) | 89 (29.8%) | 27 (39.7%) | |||
| BMI | Normal | 14 (42.4%) | 6 (33.3%) | 0.53 | 134 (45.1%) | 26 (38.2%) | 0.30 |
| Overweight or obese | 19 (57.6%) | 12 (66.7%) | 0.46 | 163 (54.9%) | 42 (61.8%) | 0.49 | |
| CV and metabolic diseases | Absence | 13 (39.4%) | 9 (50.0%) | 110 (36.8%) | 22 (32.3%) | ||
| Presence | 20 (60.6%) | 9 (50.0%) | 189 (63.2%) | 46 (67.6%) | |||
| Hypnotics intake | No | 29 (87.9%) | 16 (88.9%) | 0.99* | 235 (78.6%) | 58 (85.3%) | 0.21 |
| Yes | 4 (12.1%) | 2 (11.1%) | 64 (21.4%) | 10 (14.7%) | |||
| Fatigue scale | T1: [0–4] | 18 (56.3%) | 4 (22.2%) | 0.02 | 91 (31.5%) | 12 (17.9%) | 0.03 |
| T2+T3: [5–14] | 14 (43.8%) | 14 (77.8%) | 198 (68.5%) | 55 (82.1%) | |||
| Depression (BDI scale) | Non-depressed : <11 | 26 (81.25%) | 9 (60.0%) | 0.16* | 208 (73.8%) | 39 (59.09%) | 0.02 |
| Depressed: >11 | 6 (18.75%) | 6 (40.0%) | 74 (26.2%) | 27 (40.91%) | |||
| Night-time sleep | (hour) | 7 [5–9] | 7 [3.5–10] | 0.97** | 7 [4–10] | 7 [3.5–10] | 0.49** |
| Day-time sleep | (hour) | 10 [0–90] | 35 [0–180] | 0.006** | 15 [0–120] | 30 [0–180] | <0.0001** |
| Naps | Yes | 11 (35.5%) | 12 (70.6%) | 0.02 | 149 (52.5%) | 48 (75.0%) | 0.001 |
| No | 20 (64.5%) | 5 (29.4%) | 135 (47.5%) | 16 (25.0%) | |||
| Total sleep duration | Day+night | 7.1 [5.0–9.5] | 7.6 [4.2–10.5] | 0.25** | 7.5 [4.2–11.0] | 7.7 [4.1–11.0] | 0.39** |
| Time in bed | (Hour) | 8 [6–9] | 8 [6–10] | 0.99** | 8 [5–12.5] | 8 [5–12] | 0.42** |
| Sleep efficiency | (%) | 87.5 [62.5–100] | 88.2 [43.8–100] | 0.80** | 87.5 [33.3–100] | 87.5 [53.8–100] | 0.92** |
| WASO | (Hour) | 1 [0–3] | 1 [0–4.5] | 0.45** | 1 [0–8] | 1 [0–4] | 0.84** |
| Insomnia severity | <7 | 26 (78.8%) | 8 (44.4%) | 0.013 | 165 (55.6%) | 26 (38.8%) | 0.013 |
| >7 | 7 (21.2%) | 10 (55.6%) | 132 (44.4%) | 41 (61.2%) | |||
| RLS | 4 signs | 3 (9.4%) | 1 (5.6%) | 0.99* | 46 (15.6%) | 16 (23.5%) | 0.12 |
| Less than 4 signs | 29 (90.6%) | 17 (94.4%) | 248 (84.4%) | 52 (76.5%) | |||
| RBD | No | 26 (96.7%) | 9 (69.2%) | 0.03* | 201 (88.2%) | 46 (83.6%) | 0.37 |
| Yes | 1 (3.7%) | 4 (30.8%) | 27 (11.8%) | 9 (16.4%) | |||
| Risk of apnea | No | 16 (66.7%) | 10 (58.8%) | 0.61 | 122 (59.8%) | 28 (54.9%) | 0.52 |
| Yes | 8 (33.3%) | 7 (41.2%) | 82 (40.2%) | 23 (45.1%) | |||
*
Fisher exact test.
**
Wilcoxon rank test.
The bold values mean that the result is significant with a p-value < 0.05.