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. Author manuscript; available in PMC: 2017 Oct 3.
Published in final edited form as: J Matern Fetal Neonatal Med. 2015 Dec 7;29(15):2414–2422. doi: 10.3109/14767058.2015.1094049

Table 2.

Clinical characteristics and pregnancy outcomes of 64 cases with spontaneous early preterm delivery (<30 weeks of gestation) according to results of the MMP-8 bedside test

Characteristic MMP-8 bedside test Positive (n=27) MMP-8 bedside test Negative (n=37) P-value
Mean maternal age, years (±SD) 33.8 ± 4.5 35.6 ± 4.4 NS
Nulliparity 7 (25.9%) 8 (21.6%) NS
History of spontaneous preterm delivery 1 (3.7%) 5 (13.5%) NS
Median gestational age at amniocentesis, weeks (range) 18.0 (15.6–22.3) 17.6 (15.6–21.7) NS
Median gestational age at delivery, weeks (range) 21.0 (16.6–29.6) 24.4 (17.2–29.7) NS
Indication for delivery NS
 • Preterm labor 10 (37.0%) 17 (45.9%)
 • PROM 15 (55.6%) 17 (45.9%)
 • Cervical insufficiency 0 (0.0%) 3 (8.1%)
 • Spontaneous abortion 2 (7.4%) 0 (0.0%)
Median amniocentesis-to-delivery interval, day (range) 16 (0–95) 42 (2–91) 0.011
 • Time from amniocentesis to delivery ≤1week 6 (22.2%) 2 (5.4%) NS
 • Time from amniocentesis to delivery ≤2weeks 11 (40.7%) 2 (5.4%) 0.001
 • Time from amniocentesis to delivery ≤4weeks 17 (63.0%) 9 (24.3%) 0.004

MMP = Matrix metalloproteinase; SD = Standard deviation; NS = Not significant; PROM = Premature rupture of the membranes

Data are presented as median (range) or n (%).