Table 2.
Characteristic | MMP-8 bedside test Positive (n=27) | MMP-8 bedside test Negative (n=37) | P-value |
---|---|---|---|
Mean maternal age, years (±SD) | 33.8 ± 4.5 | 35.6 ± 4.4 | NS |
Nulliparity | 7 (25.9%) | 8 (21.6%) | NS |
History of spontaneous preterm delivery | 1 (3.7%) | 5 (13.5%) | NS |
Median gestational age at amniocentesis, weeks (range) | 18.0 (15.6–22.3) | 17.6 (15.6–21.7) | NS |
Median gestational age at delivery, weeks (range) | 21.0 (16.6–29.6) | 24.4 (17.2–29.7) | NS |
Indication for delivery | NS | ||
• Preterm labor | 10 (37.0%) | 17 (45.9%) | |
• PROM | 15 (55.6%) | 17 (45.9%) | |
• Cervical insufficiency | 0 (0.0%) | 3 (8.1%) | |
• Spontaneous abortion | 2 (7.4%) | 0 (0.0%) | |
Median amniocentesis-to-delivery interval, day (range) | 16 (0–95) | 42 (2–91) | 0.011 |
• Time from amniocentesis to delivery ≤1week | 6 (22.2%) | 2 (5.4%) | NS |
• Time from amniocentesis to delivery ≤2weeks | 11 (40.7%) | 2 (5.4%) | 0.001 |
• Time from amniocentesis to delivery ≤4weeks | 17 (63.0%) | 9 (24.3%) | 0.004 |
MMP = Matrix metalloproteinase; SD = Standard deviation; NS = Not significant; PROM = Premature rupture of the membranes
Data are presented as median (range) or n (%).