Table 1.
Clinical characteristics of the study population according to the presence or absence of meconium aspiration syndrome in the context of meconium-stained amniotic fluid
| Meconium Aspiration Syndrome | P value | ||
|---|---|---|---|
| Absence N=106 |
Presence N=12 |
||
| Maternal age (years)* | 31 (25–44) | 32(27–38) | 0.655 |
| Nulliparity (%) | 78.3 (83/106) | 100.0 (12/12) | 0.120 |
| Indications for cesarean delivery (%) | 0.056 | ||
| Previous cesarean delivery | 14.2 (15/106) | 0.0 (0/12) | |
| Failure to progress | 66.0 (70/106) | 50.0 (6/12) | |
| Fetal malpresentation | 3.8 (4/106) | 0.0 (0/12) | |
| Non-reassuring FHR pattern | 12.3 (13/106) | 41.7 (5/12) | |
| Other | 3.8 (4/106) | 8.3 (1/12) | |
| Presence of labor at amniocentesis (%) | 76.4 (81/106) | 91.7 (11/12) | 0.461 |
| Gestational age at delivery (weeks)* | 40.4 (38.0–42.7) | 40.4 (39.4–42.0) | 0.742 |
| Birth weight (g)* | 3445 (2160–4520) | 3660 (2800–4850) | 0.134 |
| Infant male gender (%) | 56.6 (60/106) | 91.7 (11/12) | 0.026 |
| Apgar score <7 (%) | |||
| 1 minute | 13.2 (14/106) | 25.0 (3/12) | 0.377 |
| 5 minute | 0.9 (1/106) | 16.7 (2/12) | 0.027 |
| Umbilical arterial pH*† | 7.238(7.014–7.409) | 7.219(6.950–7.295) | 0.175 |
| <7.00 (%) | 0.0 (0/102) | 8.3 (1/12) | 0.105 |
| <7.10 (%) | 2.9 (3/102) | 16.7 (2/12) | 0.085 |
| <7.20 (%) | 24.5 (25/102) | 41.7 (5/12) | 0.296 |
| NICU admission (%) | 2.8 (3/106) | 100.0 (12/12) | <0.001 |
| Positive amniotic fluid culture (%) | 20.4 (21/103) | 40.0 (4/10) | 0.224 |
| MMP-8 > 23 ng/mL (%) | 67.7 (67/99) | 100.0 (10/10) | 0.032 |
| Acute histologic chorioamnionitis (%) | 32.6 (28/86) | 80.0 (8/10) | 0.005 |
| Funisitis (%) | 12.6 (11/87) | 45.5 (5/11) | 0.016 |
FHR, fetal heart rate; MMP, matrix metalloproteinase; NICU, neonatal intensive care unit
*
Values are presented as the median (range).
†
Four cases without a result of an umbilical arterial blood gas analysis were excluded from analysis.