Skip to main content
. 2017 Sep 25;55(10):2983–2995. doi: 10.1128/JCM.00649-17

TABLE 1.

Fusarium spp. detected in samples from the eye

Taxon (no. of strains) Clinical relevance
 MICs (mg/liter) fora:
None Yes Unknown Amphotericin B
 Natamycin
 Terbinafine
 Voriconazole
 Isavuconazole
 ITZ PCZ CAS
Range GM MIC50 Range GM MIC50 Range GM MIC50 Range GM MIC50 Range GM MIC50
FSSC (13) 13 0.5–4 1.6 2 4–16 6.5 8 64 64 64 1–16 9.9 16 16 16 16 16 16 16
    F. falciformeb (1) 1 2 2 64 16 16 16 16 16 16
    F. keratoplasticumb (3) 3 2–4 2.5 2 4–8 5.0 4 64 64 64 8–16 10.1 8 16 16 16 16 16 16
    F. petroliphilumb (6) 6 0.5–2 1.3 1 4–8 7.13 8 64 64 64 4–16 11.3 16 16 16 16 16 16 16
    F. solanib (1) 1 2 2 16 16 64 16 16 16 16 16 16
    FSSC 9c (1) 1 1 1 4 4 64 1 1 16 16 16 16
    FSSC 25c (1) 1 2 2 4 4 64 16 16 16 16 16 16
F. oxysporum SC (6) 3 3 0.5–2 1 1 4–8 4.5 4 2–8 3.6 2 4–16 5.0 4 8–16 14.3 16 16 16 16
FFSC (3) 1 2 12 1.6 2 4–8 6.3 8 0.5–8 1.6 1 4–8 6.3 8 16 16 16 16 16 16
    F. lactis complex (1) 1 2 2 4 4 8 8 8 16 16 16 16
    F. proliferatum (2) 1 1 1–2 1.4 1 8 8 8 0.5–1 0.7 0.5 4–8 5.7 4 16 16 16 16 16 16
a

ITZ, itraconazole; PCZ, posaconazole; CAS, caspofungin; GM, geometric mean; MIC50, cumulative MIC for 50% of the isolates tested. High off-scale MICs/MECs were raised to the next highest concentration.

b

These species were previously reported as FSSC 1 (Fusarium petroliphilum), FSSC 2 (F. keratoplasticum), FSSC 3+4 (F. falciforme), and FSSC 5 (F. solani).

c

Unnamed but numbered phylogenetic species. FSSC, Fusarium solani species complex; FOSC, Fusarium oxysporum species complex; FFSC, Fusarium fujikuroi species complex.