TABLE 2.
Detailed characteristics of confirmed cases
| JMRZ no. | Isolate | Origin of isolate | Age (yr) | Sex | Symptoms | Contact lens? | Type of contact lens | Gardening/livestock | Antifungal treatment |
Outcome | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Topical | Invasivea | Systemic | ||||||||||
| JMRC:NRZ:0012 | Fusarium petroliphilum | Corneal swab | 57 | Female | Endophthalmitis | Yes | Soft | Yes | Amphotericin B, voriconazole, natamycin | Voriconazole | Amphotericin B, voriconazole | Keratoplasty |
| JMRC:NRZ:0017 | F. petroliphilum | Anterior chamber | 56 | Male | Endophthalmitis | Yes | Unknown | Unknown | Voriconazole, amphotericin B, natamycin | Amphotericin B | Amphotericin B, voriconazole, posaconazole, terbinafin | Keratoplasty |
| JMRC:NRZ:0059 | F. petroliphilum | Corneal swab | 20 | Male | Endophthalmitis | Yes | Soft | Unknown | Yes, unspecified substances | Yes, unspecified substances | Yes, unspecified substances | Enucleation |
| JMRC:NRZ:0086 | F. petroliphilum | Corneal scraping | 50 | Male | Endophthalmitis | Yes | Soft | Yes | Voriconazole, amphotericin B | Voriconazole, amphotericin B | Voriconazole, amphotericin B | Keratoplasty, enucleation |
| JMRC:NRZ:0106b | F. petroliphilum | Corneal swab | 38 | Female | Keratitis | Yes | Soft | Unknown | Voriconazole, natamycin | Voriconazole, amphotericin B | Voriconazole, amphotericin B | Keratoplasty |
| JMRC:NRZ:0575 | F. petroliphilum | Corneal swab | 58 | Male | Endophthalmitis | Unknown | Unknown | Unknown | Voriconazole | Unknown | Amphotericin B | Keratoplasty |
| JMRC:NRZ:0049c | Fusarium keratoplasticum | Corneal swab | 60 | Female | Endophthalmitis | Yes | Soft | Unknown | Voriconazole, amphotericin B | Voriconazole | Voriconazole, posaconazole | Keratoplasty, enucleation |
| JMRC:NRZ:0131 | F. keratoplasticum | Corneal swab | 26 | Female | Unknown | Unknown | Unknown | Unknown | Unknown | Unknown | Unknown | Keratoplasty |
| JMRC:NRZ:0163; JMRC:NRZ:0164 | F. keratoplasticum | Contact lens; corneal swab | 77 | Female | Keratitis | Yes | Unknown | Unknown | Voriconazole, amphotericin B | None | Amphotericin B | Restored to normal |
| JMRC:NRZ:0138 | Fusarium falciforme | Corneal swab | 58 | Female | Keratitis | No | Unknown | Unknown | Amphotericin B, natamycin | Unknown | Voriconazole | Unknown |
| JMRC:NRZ:0205 | Fusarium solani | Vitreous body | 25 | Female | Endophthalmitis | Yes | Unknown | Unknown | Voriconazole | Amphotericin B | Amphotericin B | Keratoplasty |
| JMRC:NRZ:0233 | FSSC 9d | Unspecified | 27 | Female | Endophthalmitis | Yes | Soft | Yes | Natamycin, voriconazole | Amphotericin B, voriconazole | Voriconazole | Restored to normal |
| JMRC:NRZ:0061 | FSSC 25d | Corneal swab | 47 | Female | Endophthalmitis | Yes | Soft | Unknown | Voriconazole, amphotericin B | Voriconazole | Voriconazole | Keratoplasty |
| JMRC:NRZ:0548 | Fusarium lactis complex | Contact lens disinfectant solution | 23 | Female | Keratitis | Yes | Soft | Yes | Amphotericin B, fluconazole | None | None | Restored to normal |
| JMRC:NRZ:0202 | Fusarium proliferatum | Anterior chamber | 56 | Female | Endophthalmitis | Unknown | Unknown | Unknown | Amphotericin B, voriconazole | Unknown | Unknown | Unknown |
a
Invasive antifungal treatment includes lavage of the anterior chamber and/or instillation into the vitreous body.
b
Patient committed suicide during therapy.
c
Case report published (3).
d
Unnamed but numbered phylogenetic species.