TABLE 4.

Sensitivity and specificity of HR6 for active pulmonary TB detection, stratified by HIV coinfection and smear status

PTB global cohort (n = 569) HIV status	HR6 positive (no. positive/total no.)	% sensitivity (95% CI)	% specificity (95% CI)
HIV negative (n = 403)
Culture-positive TB	156/177	88.1 (80.8–92.1)
Smear positive	132/142	93.0 (85.2–95.0)
Smear negative	24/35	68.6 (62.9–80.0)
Non-TB	24/226		89.4 (85.8–90.1)
HIV positive (n = 166)
Culture-positive TB	76/85	89.4 (82.3–91.8)
Smear positive	62/68	91.2 (85.3–92.6)
Smear negative	14/17	82.4 (70.6–88.2)
Non-TB	14/81		82.7 (72.8–87.7)