TABLE 3.
Association between bacterial phenotype and clinical cured status
| Parameter | Complete cohort (n = 104) |
Lower-extremity cohort (n = 70) |
||||||
|---|---|---|---|---|---|---|---|---|
| No. (%) of patients in: |
Odds ratio for cured (95% confidence interval) | P valuea | No. (%) of patients in: |
Odds ratio for cured (95% confidence interval) | P valuea | |||
| “Not-cured” group | “Cured” group | “Not-cured” group | “Cured” group | |||||
| Biofilm formation | 0.059††† | 0.031††† | ||||||
| None | 3 (9.7) | 28 (90.3) | 3 (12.5) | 21 (87.5) | ||||
| Weak | 7 (17.9) | 32 (82.1) | 0.49 (0.08;2.43) | 6 (23.1) | 20 (76.9) | 0.48 (0.07;2.64) | ||
| Intermediate | 5 (22.7) | 17 (77.3) | 0.36 (0.05;2.19) | 4 (36.4) | 7 (63.6) | 0.25 (0.03;1.96) | ||
| Strong | 4 (33.3) | 8 (66.7) | 0.21 (0.03;1.62) | 4 (44.4) | 5 (55.6) | 0.18 (0.02;1.51) | ||
| Antibiotic resistanceb | ||||||||
| Methicillin | 0.33 (0.06;1.29) | 0.082†† | 0.54 (0.14;2.16) | 0.529† | ||||
| No | 3 (8.8) | 31 (91.2) | 3 (16.7) | 15 (83.3) | ||||
| Yes | 16 (22.9) | 54 (77.1) | 14 (26.9) | 38 (73.1) | ||||
| Aminoglycosides | 0.17 (0.04;0.56) | <.001†† | 0.051†† | |||||
| No | 5 (7.9) | 58 (92.1) | 5 (14.3) | 30 (85.7) | 0.32 (0.08;1.17) | |||
| Yes | 14 (34.1) | 27 (65.9) | 12 (34.3) | 23 (65.7) | ||||
a
†, chi-square test; ††, Fisher's exact test; †††, Cochran-Armitage trend test.
b
Not all antibiotic resistances are listed. Others tested showed no statistical significance.