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. 2017 Jul 1;11(3):199–208.

Table 2.

Uni- and Multivariate Fine&GrayCompetingRiskRegressionAnalyses for Relapse and NRM

Relapse NRM
Univariate competing
risk regression
Multivariate competing
risk regression
Univariate competing risk
regression
Multivariate competing
risk regression
SHR
(95% CI)
p SHR
(95% CI)
p SHR
(95% CI)
p SHR
(95% CI)
p
Age 0.98 (0.97-0.99) 0.001 1.00 (0.99-1.01) 0.19 1.00 (0.99-1.02) 0.460
Sex Matching Sex matched 1(Ref.) 1(Ref.) 1(Ref.) 1(Ref.)
Male to female 0.64 (0.49-0.83) 0.001 0.67 (0.48-0.93) 0.019 1.14 (0.70-1.84) 0.598 1.30 (0.80-2.11) 0.29
Female to male 0.75 (0.58-0.96) 0.023 0.90 (0.66-1.22) 0.514 2.48 (1.68-3.67) 0.000 2.59 (1.70-3.95) 0.000
cGvHD No 1(Ref.) 1(Ref.) 1(Ref.) 1(Ref.)
Limited 0.66 (0.51-0.86) 0.002 0.64 (0.47-0.89) 0.007 0.92 (0.47-1.81) 0.812 0.89 (0.45-1.76) 0.742
Extensive 0.30 (0.24-0.39) 0.000 0.31 (0.23-0.41) 0.000 2.04 (1.28-3.27) 0.003 1.70 (1.04-2.78) 0.034
CMV Risk Low 1(Ref.) 1(Ref.) 1(Ref.)
intermediate .83 (0.40-1.74) 0.63 0.85 (0.43-1.69) 0.639 0.92 (0.28-3.01) 0.886
High 0.59 (0.39-0.89) 0.012 0.61 (0.41-0.89) 0.012 0.66 (.35-1.26) 0.215
Primary
Disease
ALL 1(Ref.) 1(Ref.) 1 (Ref.)
AML 0.46 (0.38-0.57) 0.000 0.45 (0.34-0.59) 0.000 1.12 (0.79-1.6) 0.520
CMV No 1(Ref.) 1 (Ref.) 1(Ref.)
Yes 1.00 (0.81-1.25) 0.94 1.54 (1.09-2.20) 0.015 1.62 (1.11-2.38) 0.013
aGvHD No & I 1(Ref.) 1(Ref.) 1 (Ref.) 1(Ref.)
II & III 0.87 (0.71-1.06) 0.166 0.88 (0.69-1.14) 0.350 1.74 (1.23-2.48) 0.002 1.29 (.88-1.90) 0.19
Donor
Type
Full Matched
Sibling
1(Ref.) 1 (Ref.)
Others 0.84 (0.54-1.31) 0.455 0.52 (0.19-1.42) 0.203

NRM, Non-Relapse Mortality; SHR, Sub-Distribution Hazard Ratio