Table 1.
Cancer sites among Iranian families with familial colorectal cancers in both FCC-X and MMR deficient subsets
| Cancer site | FCC-X families |
MMR deficient
families |
Sum | ||
|---|---|---|---|---|---|
| Frequency | Percent | Frequency | Percent | ||
| Colorectal | 55 | 39.3 | 31 | 67.4 | 86 |
| Stomach | 14 | 10.0 | 4 | 8.7 | 18 |
| Lung | 12 | 8.6 | 2 | 4.3 | 14 |
| Breast | 11 | 7.9 | 1 | 2.2 | 12 |
| Brain | 9 | 6.4 | 0 | 0.0 | 9 |
| Hepatobiliary tract | 7 | 5.0 | 2 | 4.3 | 9 |
| Intestine | 6 | 4.3 | 0 | 0.0 | 6 |
| Prostate | 4 | 2.9 | 2 | 4.3 | 6 |
| Uterus | 4 | 2.9 | 1 | 2.2 | 5 |
| Skin | 3 | 2.1 | 0 | 0.0 | 3 |
| Hematopoietic system | 3 | 2.1 | 3 | 6.5 | 6 |
| Bladder | 3 | 2.1 | 0 | 0.0 | 3 |
| Thyroid | 2 | 1.4 | 0 | 0.0 | 2 |
| Testis | 2 | 1.4 | 0 | 0.0 | 2 |
| Bone | 2 | 1.4 | 0 | 0.0 | 2 |
| Kidney | 1 | 0.7 | 0 | 0.0 | 1 |
| Pancreas | 1 | 0.7 | 0 | 0.0 | 1 |
| Nasopharynx | 1 | 0.7 | 0 | 0.0 | 1 |
| Total | 140 | 100 | 46 | 100 | 186 |
FCC-X: Familial colorectal cancer type X; MMR: Mismatch-repair